Respiratory Physiology Mechanics of Breathing The processes of inspiration (breathing in) and expiration (breathing out) are vital for providing oxygen to tissues and removing carbon dioxide from the body. Inspiration occurs via active contraction of muscles – such as the diaphragm – whereas expiration tends to be passive, unless it is forced. Now, let's look at the physiology of ventilation – the process of inspiration and expiration, how this differs between quiet and forced breathing. The Lungs and Breathing The space between the outer surface of the lungs and inner thoracic wall is known as the pleural space. This is usually filled with pleural fluid, forming a seal which holds the lungs against the thoracic wall by the force of surface tension. This seal ensures that when the thoracic cavity expands or reduces, the lungs undergo expansion or reduction in size accordingly. During breathing, the contraction and relaxation of muscles acts to change the volume of the thoracic cavi...
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