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Showing posts with the label Drugs and Pharmacology

Tetracycline

 Pharmacology of Tetracycline Introduction       Tetracycline, sold under the brand name Sumycin among others, is an oral antibiotic in the tetracyclines family of medications, used to treat a number of infections, including acne, cholera, brucellosis, plague, malaria, and syphilis. Common side effects include vomiting, diarrhea, rash, and loss of appetite.  Formula :  C 22 H 24 N 2 O 8 IUPAC ID :  (4S,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide Molar mass :  444.435 g/mol CAS ID :  60-54-8 Elimination half-life :  8–11 hours, 57–108 hours (kidney impairment) Metabolism :  Not metabolized DOSAGES OF TETRACYCLINE Capsule / Tablet 250  mg 500 mg Syrup (extemporaneously prepared) 125mg/5mL 5 mg Dosage Considerations – Should be Given as Follows: Chronic Bronchitis ,  Acute   Exacerbation 500 mg orally every 6 hours Acne 250-50...

What is Pharmacology?

 Pharmacology Introduction Pharmacology is a branch of medicine, biology and pharmaceutical sciences concerned with drug or medication action, where a drug may be defined as any artificial, natural, or endogenous molecule which exerts a biochemical or physiological effect on the cell, tissue, organ, or organism. Pharmacology research is also a critical component in the development of modern 'personalized medicine'. There are many sub-specialties within the general discipline of pharmacology. Pharmacodynamics is the study of the effects of drugs on biological systems and specifically addresses the chemical properties and physiological and behavioral effects of drugs arising from their interaction with molecular targets such as receptor proteins or enzyme systems. In contrast, pharmacokinetics is the study of what biological systems do to the drug and encompasses investigations of drug absorption, distribution, biotransformation and excretion, essential information for the design...

METRONIDAZOLE (FLAGYL)

  METRONIDAZOLE INTRODUCTION AND CHEMISTRY Metronidazole, an antibiotic and antiprotozoal medication. It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis.  Formula: C6H9N3O3 Molar mass: 171.16 g/mol CAS ID: 443-48-1 PubChem CID: 4173 Adult and Pediatric Dosage Forms and Strengths Capsule 375mg Tablet 250 mg 500 mg Tablet, extended-release 750 mg Infusion solution 500 mg/100mL What Are Side Effects Associated with Using Metronidazole? Common Side effects of Metronidazole include: Appetite loss Yeast infection (candidiasis) Diarrhea Dizziness Headache Nausea Vomiting Loss of control of bodily movements Dark urine Disulfiram-type reaction with ethanol Furry tongue Hypersensitivity Low white blood cell count (neutropenia) Metallic taste Neuropathy Pancreatitis Seizures Blood clot (thrombophlebitis) Dry mouth Brain disease (encepha...